Being Overweight Increases Risk of Deadliest Breast Cancer

Research has shown that obesity raises the risk of breast cancers caused by estrogen.Rift Gold But a new study suggests that gaining too much weight may also factor in to a much deadlier and more aggressive form of the disease.

Overweight and obese women were 35 percent more likely to get the often lethal triple-negative breast cancers than average-weight and thin women, according to the findings published in the journal Cancer Epidemiology, Biomarkers & Prevention.

RIFT PlatinumThe more dangerous type of the disease is also less common than other kinds, accounting for about 10 to 20 percent of breast cancer cases, Reuters reported.

"The fact that we found an association with triple-negative breast cancer is unique because, rift goldbiologically, this subtype is very different from other breast cancers," author Amanda Phipps of the Fred Hutchinson Cancer Research Center in Philadelphia told Reuters.

Phipps and her team looked at the records of 155,723 women participating in a large-scale study on the impact of hormone replacement therapy as a treatment for menopause.

They compared the body mass index (BMI) and physical activity levels of the 307 women who had triple-negative breast cancer with that of the 2,RIFT Platinum610 women who had estrogen receptor-positive breast cancer.

They found that those with the highest BMI had a 35 percent greater risk of triple-negative breast cancers and a 39 percent higher risk of those triggered by estrogen.

The majority of breast tumors develop because of an excess of the hormone estrogen and are classified as estrogen-receptor positive. Other types are fueled by progesterone or a protein called HER2.TERA Gold Those forms of the illness are easily treatable when caught early.

But a fourth kind of breast cancer, known as triple-negative, has no estrogen, progesterone or HER2 receptors -- hormones and proteins that are vital for most breast cancer drugs to be effective.

Previous research has shown that when women gain too much weight, their chance of breast cancer shoots up, probably because estrogen builds up in the fat.